CP-866087 - An Overview

CP-866087 - An Overview

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Contraindicated (1)bortezomib will boost the level or effect of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Strong or reasonable CYP2C19 inhibitors may well raise mavacamten systemic exposure, resulting in coronary heart failure because of systolic dysfunction.

Crucial: The drug information on this webpage is meant to become educational. It isn't a substitute for health-related suggestions. The knowledge may not include all achievable makes use of, actions, interactions, or Uncomfortable side effects of this drug, or precautions to be taken while using it.

Acute respiratory distress syndrome (ARDS) and acute diffuse infiltrative pulmonary sickness of not known etiology for instance pneumonitis, interstitial pneumonia, lung infiltration have occurred

– Michael Cramer Could four, 2009 at 0:fifteen five Clearer, Sure, but that wouldn't show the "positional" nature of redirection. The instance is contrived since it's not normally helpful To achieve this in just one line - the strategy results in being actually practical when distinct functions are accountable for the various portions of the redirection. For instance, each time a script does a person little bit of redirection and also you run it with One more bit.

acetazolamide will improve the level or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.

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ceritinib will increase the stage or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

tecovirimat will boost the amount Retene or effect of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is usually a 2' weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse consequences if coadministered with sensitive substrates of these enzymes.

To watch formulary data very first create a listing of programs. Your list might be saved and may be edited Anytime.

I also advocate looking through this article on mistake redirecting exactly where this topic is roofed in complete detail.

Bortezomib is in a class of medicines referred to as antineoplastic agents. It really works by killing most cancers cells.

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verapamil will improve the amount or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Bortezomib therapy needs a collaborative effort with the interprofessional Health care team. The drug might cause hypotension, as well as the nurse must Check out the BP frequently. Nursing staff members must report any indications of adverse events on the attending clinician immediately and Check out Using the pharmacist. If you will discover any questions on the Retene drug, 1 really should consult Together with the pharmacist to start with.